Medical Degree Program in China - Pharmacology

1. Introduction

Pharmacology is a subject that studies the interaction and its law and mechanism of action between drug and the body (including pathogens). Pharmacology mainly refers to the study of the caused change mechanism of body function when using chemical substances to treat diseases. It is sometimes difficult to strictly distinguish drug with toxic difficult, pharmacology, in fact; also takes poison as the research object, so the application of pharmacology in particular about medical treatment is called pharmaceutical, with poison as the research object is called toxicology.
2 Tasks
The mission of pharmacology is to provide theoretical basis for clarifying the drug effect and mechanism and improving the quality of the drug and improve the efficacy of drug, prevention and treatment of adverse reactions; to provide the experimental data for research and development of new drug and finding new use in medicine and cell physiological and pathological process. The pharmacological approach is experimental, that is, to observe the action of the drug on the body or its components under the condition of strict control and analyze the principle of the objective function. In recent years, gradual development and establishment of clinical pharmacology takes clinical patient as the object of research and service of applied science, the task is putting the pharmacology theory into clinical medicine technology, that is, transform pharmacological effect into the actual effect, which are subsequent sections of the pharmacological basis. The main purpose of learning pharmacology is to understand the role of drug, mechanism and how to give full play to its clinical efficacy, to theory and practice to understand the effect of drug in the process of the cause and effect relationship.
Three major tasks of pharmacology or three categories:
First, pharmacology is a compulsory course in medical colleges and universities, to guide clinical drug use;
Second, evaluate drug efficacy and the difference in economy and other aspects.
Third, pharmacology is an important part of life science.
3. Research Content
Pharmacology is a bridge between basic medicine and clinical medicine, medicine and pharmacy. Clinical practice is carried out under the guidance of the theory of pharmacology, and enriches the theory of pharmacology on the basis of experimental study. Drug research and application in addition to respect the laws of science, but also is in accordance with the provisions of laws, regulations and related guidelines, in order to protect people's lives and health.
The contents of pharmacology include:
(1) pharmacodynamics: Study the effect of drug on the body, including the function and effect of drug, mechanism and clinical application.
(2) pharmacokinetics: Study the changes and rules of drug in the role of the body, including drug in vivo absorption, distribution, metabolism and excretion processes, especially blood drug concentration changes with time changes, the impact of drug efficacy of factors.
4. Clinical Pharmacology
Clinical pharmacology is a subject to study the law of the interaction between drug and human body. It is not only the final synthesis of pharmacological studies, but also a new branch of pharmacology. The main feature distinguished from the basic pharmacological research is that clinical pharmacology research is carried out in the human body. Clinical pharmacology research is one of the most important contents in the evaluation of new drug.
5. Main Task of Clinical Pharmacology Research in New Drug Evaluation 
1). To observe the effect of new drug on human and toxicity and study the transport and transformation rules of new drug in the body.
2). Long-term in-depth clinical observation on the efficacy and toxicity of new drug, which is a regular work of clinical pharmacology research.
6. Main Duties of Clinical Pharmacology Staff
(1). Be responsible for new drug clinical pharmacology research, actively take some medicines and chemical reagents clinical pharmacological research work, have a responsibility to guide and assist the local clinical hospital to carry out and do a good job of new drug clinical test and verify in technology.
(2) Finish clinical reevaluation on produced drug, the clinical pharmacology base should actively carry out reevaluation of marketed drug that they undertake, For the drug that the effect is not correct or with adverse reactions or other reasons harm people's health, social investigation, data collection should be taken combined with the actual situation of unit, combined with experimental research, analysis and adjustment, make scientific conclusions.
(3) Be responsible for drafting all kinds of drug clinical test indexes and evaluation principles of the clinical pharmacology base responsible for drafting all kinds of drug clinical trials and clinical validation requirements, content and outcome measures, clinical evaluation principles, clinical study of drug reach the requirements of standardization.
(4) To guide the clinical medication to carry out the monitoring of adverse drug reactions, improve the level of drug treatment.
(5) For clinical research on new drug and doctors of clinical pharmacology professional knowledge training.
(6) To carry out clinical pharmacology consulting and information exchange of information on the clinical pharmacology base, should actively carry out clinical pharmaceutical consultation, conditional units deal with the open society.
(7) Temporary tasks and temporary clinical pharmacology tasks assigned by the health institutes.
7. Pharmacology of New Drug
A new drug is a drug that is different from the existing drug in the chemical structure, the drug component, or the pharmacological action.
8. Pharmacology of Traditional Chinese Medicine
Pharmacology of traditional Chinese medicine takes the basic theory of traditional Chinese medicine as a guide, studies the effect of Chinese medicine on the body's various functions and its action principle by using pharmacological methods. It focuses on traditional Chinese medicine theory and the modern science of TCM research results, through research and experiments to understand pharmacological studies of the profile. The purpose of the research on the pharmacology of traditional Chinese medicine is mainly to make the medical workers know the function principle of the disease prevention and treatment, and the material basis of the curative effect. Pharmacology of traditional Chinese medicine is an important part in the pharmaceutical category.
9. Basic Theory
Pharmacological effects
Therapeutic effects of drug
Adverse reactions of drug
10. Dose Effect Relationship
reaction curve
Drug safety evaluation
Action mechanism drug
Receptor theory
Pharmacokinetics of drug

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Anhui Medical University

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